Stephen W. Chung, MD PhD FRCSC

Professor, UBC – Division of General Surgery
Scientific Director, BC Transplant Society

Head Hepatobiliary & Pancreatic Surgery Vancouver General Hospital
Active Staff, Vancouver General Hospital

City: Vancouver
Hospital Authority: Vancouver Coastal Health

Clinical office Address:
Gordon & Leslie Diamond Health Care Center
5th floor, 2775 Laurel Street
Vancouver, BC V5Z 1M9

Clinical Office Phone: 604-875-4459  
Clinical Office Fax:  604-675-3973

Email: stephen.chung@vch.ca

Focus

  • hepatobiliary and pancreatic surgery, transplantation
  • transplant immunology

Research Interests

Dr. Chung’s academic career incorporates the principles of research and education with clinical subspecialization, developing each pathway in a complementary manner. His clinical activities focus on diseases of the liver (primarily cancer and liver transplantation), pancreas and the biliary tree.

His research has been focused upon the modulation of the immune system in animal and human studies as it relates to transplantation and cancer. Specific research interests include development of new strategies for monitoring the immune status of transplant recipients and evaluation of novel tolerance inducing regimens in different animal models of transplantation.

He is part of a transplant immunology research team funded by a grant from Genome Canada examining the gene expression profile of immune cells from transplant recipients in order to develop methods of immunomonitoring to predict transplant graft rejection or accommodation. In parallel research studies, these principles of immunological evaluation have been applied to assessment of predicting outcomes of patients undergoing surgical resections for liver and pancreatic cancer.

Dr. Chung also has educational interests in surgical sciences, especially related to liver diseases and transplantation. He is involved in undergraduate, postgraduate and continuing medical education in these areas, has established a university-wide symposium for faculty and students in transplantation, and has organized several postgraduate surgical and research educational forums. Dr. Chung heads the the Canadian Institutes of Health Research Strategic Training Program in Transplantation. This program, involving many investigators and clinicians, is also supported by the VGH & UBC Hospital Foundation, The Michael Smith Foundation for Health Research, the Vancouver Coastal Health Research Institute, and Fujisawa Canada.

He is a member a number of scholarly societies including the Canadian Association of General Surgeons, the BC Surgical Society, the American Society of Transplant Surgeons, the American Hepatopancreaticobiliary Association, the International Liver Transplantation Society, the Pacific Coast Surgical Association and the Society of University Surgeons.

Selected Publications

McKenna GJ, Meneghetti A, Mui ALF, Chen YL, McMaster WR, Scudamore CH, Ong C,
Owen DA, Chung SW:
Predictive Value of Lymph Node and Tumour Matrix Metalloproteinase Expression in the Analysis of Metastatic Periampullary Tumours. J Surgical Oncology. 2005; 15: 90:239-46.

Chang EN, Scudamore CH, Chung SW:
Transplantation: focus on kidney, liver and islet cells. Can J Surg 2004; 47:122- 129.

McKenna GJ, Meneghetti A, Chen YL, McMaster WR, Scudamore CH, Owen DA, Chung SW:
Matrix metalloproteinases in hepatocellular carcinoma: a host-tumour interaction. Am J Surg 2002; 183:588-94.

Chen YL, McKenna GJ, Hu YX, Smith RM, Ong CR, Mui AL, Chung SW:
Liver nonparenchymal cells are involved in hyporesponsiveness induced by portal vein injection of alloantigen. Immunol Lett 2002. 81:1-11.

Chung SW, Kirkpatrick AW, Kim N, Scudamore CH, Yoshida EM:
Indications for liver transplantation in British Columbia’s aboriginal population: A ten year retrospective analysis. Can J Gastro. 2000;14:775-9.