Mira Keyes, MD FRCPC

Clinical Professor
University of British Columbia (UBC)

Active Staff: Radiation Oncologist
British Columbia Cancer Agency (BCCA) – Vancouver Centre *

Head, BCCA Prostate Brachytherapy Program BC Cancer Agency (BCCA)

Active Clinical Staff – Vancouver General Hospital (VGH)

City: Vancouver
Hospital Authority: Provincial Health Services

Address: BCCA-VCC
600 West 10th Avenue
Vancouver, BC V5Z 4E6

Phone: 604.877.6000 local 2660     Fax: 604.877.0505

Email: mkeyes@bccancer.bc.ca

Major Clinical Focus –
• Prostate Brachytherapy
• Genito-Urinary Oncology
• Breast Cancer
• Postgraduate Medical Education
• Patient Communication


EDUCATION
• Medical Doctor (Medicine), University of Novi Sad, Yugoslavia, Serbia, 1986
• FRCPC Radiation Oncology, Royal College of Physicians of Canada, 1996

POSTGRADUATE TRAINING
• Fellow of The Royal College of Physicians of Canada (Radiation Oncology), Vancouver Cancer Centre 1996-1997
• MCCEE, LMCC & FMGEMS, Part I and Part II, 1990-1991
• Resident (Gynecology and Obstetrics), Institute of Oncology, Medical School, University of Novi Sad, Yugoslavia, 1987-1989
• Graduate Studies in Clinical Pharmacology, Medical School, University of Novi Sad, Yugoslavia, 1988-1989
• ABS school of Brachytherapy, 1995
• ONCOTALK course in Communication 2009, 2010

Biographic Summary ( Background, Academic Interests and Activities, Clinical Activities )

Dr. Keyes is one of the four founders of the British Columbia Cancer Agency (BCCA) Prostate Brachytherapy Program, established in 1998. Dr. Keyes is past BCCA Brachytherapy Program Quality Assurance chair. Since 2006, she is a Provincial Brachytherapy Program Head.

Dr. Keyes is a Vice-Chair of the AFC Subcommittee Diploma in Brachytherapy for the Royal College of Physicians and Surgeons of Canada.  She is a past elected board member and secretary for ABS (American Brachytherapy Society) and present ABS Chair of the Education and Schools Committee. Since 2015, Dr. Keyes is ASTRO and ABS Prostate Brachytherapy Workshops course director. In 2017, she was awarded ABS Presidents Award, for outstanding contribution to American Brachytherapy Society. She is a member of the editorial board for Brachytherapy Journal.

Dr. Keyes is a former Residency Training Program Director in Radiation Oncology at UBC, and past Royal College examiner in Radiation Oncology.  She is recipient of several UBC teaching awards including: 2017 AD McKenzie UBC Department of Surgery Clinical Teaching Award, 2016 Radiation Oncology Residency Training Program Teaching Award and 2014 CanMeds of Excellence both UBC Radiation Oncology Residency Training Program Awards.

Dr Keyes has been a keynote speaker at many national and international conferences; including ASTRO, American Brachytherapy Society, Australian Brachytherapy Group annual meetings, Seattle Prostate Institute Annual Advanced Prostate Brachytherapy Courses, MD Anderson Brachytherapy Advanced Conferences and CARO.  She is an author of over 70 peer reviewed manuscripts and recipient of many peer review grants including a CIHR grant in 2015 and Michael Smith Foundation grant in 2017 for translational research in prostate cancer.  She has a large clinical GU and breast cancer clinical practice.


PUBLICATIONS

(1)Keyes M, Merrick G, Frank SJ, Grimm P, Zelefsky MJ. American Brachytherapy Society Task Group Report: Use of androgen deprivation therapy with prostate brachytherapy-A systematic literature review. Brachytherapy 2017 Mar – Apr;16(2):245-265.

(2) Keyes M, Pickles T, Crook J, McKenzie M, Cheung A, Spadinger I, et al. Effect of aging and long-term erectile function after iodine-125 prostate brachytherapy. Brachytherapy 2015 May-Jun;14(3):334-341.

(3) Keyes M, Crook J, Morris WJ, Morton G, Pickles T, Usmani N, et al. Canadian prostate brachytherapy in 2012. Can Urol Assoc J 2013 Jan-Feb;7(1-2):51-58.

(4) Rodda S, Tyldesley S, Morris WJ, Keyes M, Halperin R, Pai H, et al. ASCENDE-RT: An Analysis of Treatment-Related Morbidity for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost with a Dose-Escalated External Beam Boost for High- and Intermediate-Risk Prostate Cancer. Int J Radiat Oncol Biol Phys 2017 Jan 6.

(5) MacAulay C, Keyes M, Hayes M, Lo A, Wang G, Guillaud M, et al. Quantification of large scale DNA organization for predicting prostate cancer recurrence. Cytometry A 2017 Dec;91(12):1164-1174.

(6) Keyes M, Macaulay C, Hayes M, Korbelik J, Morris WJ, Palcic B. DNA ploidy measured on archived pretreatment biopsy material may correlate with prostate-specific antigen recurrence after prostate brachytherapy. Int J Radiat Oncol Biol Phys 2013 Aug 1;86(5):829-834.

(7) Keyes M, Morris WJ, Spadinger I, Araujo C, Cheung A, Chng N, et al. Radiation oncology and medical physicists quality assurance in British Columbia Cancer Agency Provincial Prostate Brachytherapy Program. Brachytherapy 2013 Jul-Aug;12(4):343-355.

(8) Grimm PD, Billiet I, Bostwick DG, Dicker A. P., Frank SJ, Immerzeel J, Keyes M , et al. Comparative analysis of prostate-specific antigen free survival outcomes for patients with low, intermediate and high risk prostate cancer treatment by radical therapy. Results from the Prostate Cancer Results Study Group. BJU Int 2012;109(supp 1):22-29.


* The British Columbia Cancer Agency (BCCA)-Vancouver Centre (VC) is the largest academic cancer centre for the BCCA, located in downtown Vancouver and treating about one third of the radiation oncology cancer patients in the Province of BC. Over 4360 cancer patients are seen each year in the radiation oncology department. There are 20 Radiation Oncology (RO) physician faculty with full disease site specialization and clinical programs of excellence, 2 General Practice (Internist) Oncology Physicians, 3 Clinical Fellows and 10 RO residents. The BCCA-Vancouver Centre also has 17 physicists and a graduate training program in physics, 15 nurses, >60 radiation therapists clerks, secretaries and many others within radiation oncology. General capabilities include 9 Linacs (including Truebeam), 1 cobalt, VMAT (first developed in the BCCA-VC), IMRT, SBRT, IGRT, HDR and LDR brachytherapy suites, and Protons (at the TRIUMF centre). The Vancouver Centre radiation oncology department conducts all levels of research (basic, translational, clinical, population), and is the main educational institution in BC for the training of graduate (residents) and undergraduate (medical) students. The interdisciplinary Radiation Oncology team is part of the even larger multidisciplinary and provincial teams.